Welcome to CRBIP

The newly constituted national node of MIRRI, MIRRI FR met in the Institut Pasteur campus on October 27-28th at the same time the Agreement for MIRRI FRANCE was being signed.

On October 27 and 28, the CRBIP had the honor of hosting the General Assembly of the microbial pillar of RARe, which brought together seven microbial-domain Biological Resource Centers (mBRCs) of microorganisms from INRAe: five CIRM, the CRB-FAN and the CRB-SAMBO, as well as the biobanks from the CRBIP. The assembly featured presentations from the pillar’s ​​various partners, alongside overviews of new projects, tools, and potential future members. These discussions were followed, one week later, by the signing of the agreement to officially establish the GIS (Scientific Interest Group) "MIRRI France." This entity will serve as the foundation for the French node of MIRRI-ERIC—the European research infrastructure dedicated to microbial resources—in which the members of the RARe microbial pillar participate.

Proceedings of the Euro-African Congress on Microbial Genetic Resources Now Published

Raquel Hurtado-Ortiz and Meriem Paris, members of the RGM EuroAfrica scientific committee, are pleased to announce the publication of the actions of the 1st Euro-African Congress on the Valorization of Microbial Genetic Resources (RGM EuroAfrica).

The Congress, held from May 18 to 20, 2026, in Rabat, Morocco, was organized by the National Center for Scientific and Technical Research (CNRST), in partnership with the Moroccan Ministry of Higher Education, Scientific Research and Innovation, the Biological Resource Center of the Institut Pasteur (CRBIP, France), and the National Research Institute for Agriculture, Food and the Environment (INRAE, France).

The proceedings are now freely available and can be downloaded here.

The scientific committee hopes that this compilation will reflect the scientific quality of the presentations, the diversity of the themes addressed, and the many avenues of reflection that enriched the RGM EuroAfrica Congress.

CRBIP at MALDIBANK Webinar 1: Technology, Services & Opportunities

CRBIP is pleased to invite you to the first webinar of the MALDIBANK series, "Introducing MALDIBANK to MALDI-TOF Users: Technology, Services & Opportunities", taking place online on 26 October 2026.

MALDIBANK is a pioneering EU-funded initiative developing an open, cloud-based databank of MALDI-TOF mass spectra, combined with innovative algorithmic tools for microorganism identification. The first webinar in the MALDIBANK series will introduce the project and its relevance to current and prospective MALDI-TOF users.

As an active partner in the project, CRBIP coordinates Task 3 of Work Package 7 (WP7), dedicated to drafting a proposal for an ISO technical specification on the establishment of MALDI-TOF reference spectra for microorganism identification. This work will be presented during the webinar.

📅 Date: 26 October 2026

🕑 Time: 14:00-15:45 CET

💻 Format: Online webinar

🔗 Registration: Access here

Programme highlights

1. MALDIBANK: The Project at a Glance – Ana Portugal (MIRRI-ERIC, PT) & Michel-Yves Mistou (INRAE, FR)

2. The Technology Behind MALDIBANK – Anne-Cécile Normand (Sorbonne Université, FR)

3. The MALDIBANK Infrastructure: Cloud, HPC, FAIR & Openness – Marco Becutti (UNITO, IT)

4. MALDIBANK Database: Biodiversity & Quality – Pierre Becker (Sciensano, BE)

5. From Science to Market – Michel-Yves Mistou (INRAE, FR), Theodora Katsila (NHRF, GR) & Morgane Daumas (Institut Pasteur-CRBIP, FR)

6. Q&A session

CRBIP participated in the CATALYST kick-off meeting that took place on September 29-30 in Amsterdam

CATALYST: CRBIP will become a catalyser in the context of the new European project CATALYST to enhance research reproducibility

The newly funded Horizon Europe project CATALYST will change research culture to help reform 15 departments into "catalysers" of reproducible research, then cascade effective measures that foster culture change to as many as possible across Europe.

CRBIP participated in the XMet kick-off meeting that took place on September 7-8 in London

XMet : Metrology to ensure rapid and accurate diagnostic response to current and emerging infectious diseases

XMET will strengthen the accuracy, comparability and clinical value of infectious-disease diagnostics by providing the metrology needed to underpin confidence in testing. Current bioanalytical in-vitro diagnostic (IVD) tests, including polymerase chain reaction (PCR) and lateral flow devices, lack robust reference systems to ensure traceability and reproducibility. This project will build a comprehensive measurement infrastructure combining reference methods, well characterised materials, advanced statistics and clinical evaluation strategies. XMET will work closely with IVD manufacturers, regulators, laboratories and public health agencies to develop the metrology to support testing for routine infectious diseases and emerging pandemics threats.

A scipod on the importance of biobanking based on Target Specimen Profiles

The new prices of the CIP and PCC strains are online.

Check under Resources for more information

CRBIP delegates attended the ISO TC276 meeting at IARC (WHO) in Lyon in the context of the MALDIBANK project.

The European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) is a key component of the genomic surveillance of multidrug-resistant bacteria and, as such, plays a vital role in public health. It is coordinated by the European Centre for Disease Prevention and Control (ECDC).

This European surveillance programme, based on epidemiology and whole-genome sequencing, aims, in particular, to determine the geographic distribution and population dynamics of multidrug-resistant clones and transmissible resistance elements to inform risk assessment, prevention and control policies and to support countries in developing technical capability and proficiency for genomic-based surveillance of multidrug-resistant bacteria with epidemic potential.

To address these public health challenges, EURGen-Net currently relies on the participation of national reference laboratories (CNR) or equivalent laboratories from 34 European countries.

For the past two years, the ECDC, as part of EURGen-Net, has been contracting the expertise of the Biological Resource Centre of the Institut Pasteur (CRBIP), headed by Fay Betsou. Recognized and commissioned as a specialist central biobank, the CRBIP centralises, purifies and analyses bacterial isolates from 34 European countries for two groups of pathogens: Acinetobacter baumannii and Klebsiella pneumoniae, bacteria that have become resistant to the carbapenem class of antibiotics and/or colistin (for more information, see the box dedicated to these bacterial strains). A third group, Pseudomonas aeruginosa, will follow in 2027.

The CRBIP contributes to clarification and guidance on sharing genetic resources and the Nagoya Protocol:

Faggionato D et al. Policy Briefing: from access to use—untangling the international legal frameworks that govern microbial resources. Sustainable Microbiology. Volume 3, Issue 1, 2026, qvag005

Faggionato D et al. Policy in practice: How to do the Nagoya Protocol: common misconceptions, challenges and best practices for access and benefit-sharing compliance. Sustainable Microbiology. Volume 3, Issue 2, 2026, qvag007

The PARADIGM kick-off meeting took place on the 6th October 2024 at the Saint-Antoine Hospital in Paris (AP-HP).

Within the PARADIGM project, the Collection of Institut Pasteur (CIP) will be responsible for compiling and managing this national biobank for bacteriophages and hosting bacterial strains. The project management office ( CRBIP-PMO) will be involved in CRBIP internal coordination. The Genome Informatics and Phylogenetics Expertise Group (GIPhy) will be responsible for bioinformatics quality control of the phages and their host strains.

The PARADIGM project is supported by the French government under the France 2030 program managed by the National Research Agency (ANR), reference ANR-24-PEBI-0005. The project was selected by the ANR via its Priority Research Programs and Equipment initiative on Biotherapies – PEPR Biothérapies.